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Abstract:

Aim: was to improve the efficiency of diagnosis of patients with coronary heart disease, by estimating of possibilities of cardiac multislice computed tomography in comparison with coronary angiography.

Materials and methods: study included 64 patients (18 women and 46 men, mean age 62,4 ± 9,5 years) with a high risk of developing coronary heart disease. In 34 patients - myocardial infarction in anamnesis (18 patients - in pool right coronary artery in 16 patients - in left anterior descending artery). Clinics of angina pectoris - in 40 patients (functional class (FC) I - 10; FC II - 22, FC III - in 6, FC IV - 2 patients). Selection criteria: the absence of disease progression for at least 6 weeks, and at least 3 months of optimal treatment. All patients underwent cardiac MSCT at 256-slice CT scanner. Obtained data was compared with data of reference method - x-ray coronary angiography.

Results: comparison of MSCT coronary angiography with invasive data showed a high comparability of results of two methods in the evaluation of coronary artery disease. It was revealed that discrepancies between cardiac MSCT and CAG in detection of hemodynamically insignificant stenoses ranging from 0 to 4%, hemodynamically significant stenoses - from 0 to 2.6%, subtotal stenosis - from 0 to 1%, occlusions - 0%. The presence of strong correlations between data of cardiac MSCT and coronary angiography of stenosis, demonstrated the high quality of MSCT imaging of coronary artery segments in the examination with a variety of modes of application method.

Conclusion: multislice computed tomography is a highly effective method for diagnosing of structural and anatomic changes of coronary arteries in patients with coronary heart disease.

 

References

1.     Chazov E.I. Perspektivy kardiologii v svete progressa fundamental'noj nauki [Cardiology prospects in sight of the progress of fundamental science.]. Ter. arhiv. 2009;9:5-8 [In Russ].

2.     Kokov L.S., Shutihina I.V., Timina I.E. Ispol'zovanie ul'trazvukovyh tehnologij v ocenke ateroskleroticheskih porazhenij sosudistoj stenki [The use of ultrasonic technology in the assessment of atherosclerotic lesions of the vascular wall.]. Molekuljarnaja medicina. 2013;4:15-25 [In Russ].

3.     Sinicyn V.E., Stukalova O.V., Docenko Ju.A. i dr. Kontrastnaja magnitno-rezonansnaja tomografija v ocenke rubcovyh porazhenij miokarda u bol'nyh IBS[Contrast magnetic resonance imaging in the evaluation of myocardial scarring lesions in patients with coronary artery disease.]. Diagnosticheskaja i intervencionnaja radiologija. 2009;3 (4):23-31 [In Russ].

4.     Fedotenkov I.S., Gagarina N.V., Veselova T.N., Sinicyn V.E., Ternovoj S.K. Kolichestvennyj analiz urovnja kal'cinoza koronarnyh arterij: sravnenie informativnosti mul'tispiral'noj komp'juternoj tomografii i jelektronno-luchevoj tomografii[Quantitative analysis of the level of calcification of the coronary arteries: comparison of informativeness of multislice computed tomography and electron beam tomography.]. Terapevticheskij arhiv. 2006;12:15-19 [In Russ].

5.     Ternovoj S.K., Veselova T.N., Sinicyn V.E. i dr. Rol' mul'tispiral'noj komp'juternoj tomografii v diagnostike infarkta miokarda [The role of multislice computed tomography in the diagnosis of myocardial infarction.]. Kardiologija. 2008; 1: 4-8 [In Russ].

6.     Sinicyn V.E., Ternovoj S.K., Ustjuzhanin D.V. i dr. Diagnosticheskoe znachenie KT-angiografii v vyjavlenii gemodinamicheski znachimyh stenozov koronarnyh arterij [The diagnostic value of CT angiography in the detection of hemodynamically significant stenoses of coronary arteries]. Kardiologija. 2008; 1: 9-14 [InRuss].

7.     Ustjuzhanin D.V., Veselova T.N., Sinicyn V.E. i dr. Cravnitel'nyj analiz diagnosticheskogo znachenija neinvazivnoj angiografii koronarnyh arterij s pomoshh'ju jelektronno-luchevoj i mul'tispiral'noj komp'juternoj tomografii [Comparative analysis of the diagnostic value of noninvasive coronary angiography using the electron beam and multislice computed tomography.]. Terapevticheskij arhiv. 2008; 4:12-15[In Russ].

8.     Veselova T.N., Merkulova I.N., Mironov V.M., Merkulov E.V., Ternovoj S.K., Ruda M.Ja. Neinvazivnaja ocenka ateroskleroticheskogo porazhenija koronarnyh arterij u bol'nyh s ostrym koronarnym sindromom metodom mul'tispiral'noj komp'juternoj tomografii[Noninvasive assessment of atherosclerotic lesions of coronary arteries in patients with acute coronary syndrome by multislice computed tomography.]. Medicinskaja vizualizacija. 2010; 4:100-109 [In Russ].

9.     Petcherski O., Gaspar T., Halon D. et al. Diagnostic accuracy of 256-row computed tomographic angiography for detection of obstructive coronary artery disease using invasive quantitative coronary angiography as reference standard. Am. J. Cardiol. 2013;111:510-515.

10.   Gaudio C., Pelliccia F., Evangelista A. et al. 320-row computed tomography coronary angiography vs. conventional coronary angiography in patients with suspected coronary artery disease: a systematic review and metaanalysis. Int. J. Cardiol. 2013;168:1562-1564.

11.   Fedotenkov I.S., Veselova T.N., Ternovoj S.K., Sinicyn V.E. Rol' mul'tispiral'noj komp'juternoj tomografii v diagnostike kal'cinoza koronarnyh arterij [The role of multislice computed tomography in the diagnosis of coronary artery calcification]. Kardiologicheskij vestnik. 2007; 11 (XIV): 45-48 [In Russ].

12.   Ternovoj S.K., Nikonova M.Je., Akchurin R.S. i dr. Vozmozhnosti mul'tispiral'noj komp'juternoj tomografii (MSKT) v ocenke koronarnogo rusla i ventrikulografii v sravnenii s intervencionnoj koronaroventrikulografiej [Possibilities of multislice computed tomography (MSCT) in the evaluation of coronary arteries and ventriculography in comparison with interventional coronaroventriculography.]. Rossijskij jelektronnyj zhurnal luchevoj diagnostiki. 2013;3 (9): 28-36 [In Russ].

13.   Ternovoj S.K., Veselova T.N. Vyjavlenie nestabil'nyh bljashek v koronarnyh arterijah s pomoshh'ju mul'tispiral'noj kompjuternoj tomografii [Identification of unstable plaques in coronary arteries using a multislice computed tomography.]. Rossijskij jelektronnyj zhurnal luchevoj diagnostiki. 2014:4(13):7- 14 [In Russ].

14.   Sabarudin A., Sun Z. Coronary CT angiography: Diagnostic value and clinical challenges. World J. Cardiol. 2013;26;5(12):473-483.

15.   Pelliccia F., Pasceri V., Evangelista A. et al. Diagnostic accuracy of 320-row computed tomography as compared with invasive coronary angiography in unselected. consecutive patients with suspected coronary artery disease. Int. J. Cardiovasc. Imaging. 2013;29(2):443-452.

16.   Obaid D.R., Calvert PA., Gopalan D. et al. Dualenergy computed tomography imaging to determine atherosclerotic plaque composition: a prospective study with tissue validation. J Cardiovasc Comput Tomogr. 2014; 8(3):230-237. [PubMed: 24939072]

17.   Gbaid D.R., CalvertPA., Gopalan D. et al. Atherosclerotic plaque composition and classification identified by coronary computed tomography: assessment of computed tomography-generated plaque maps compared with virtual histology intravascular ultrasound and histology. Circ Cardiovasc Imaging. 2013;6(5):655-664. [PubMed: 23960215] 

18.   Stehli J., Clerc O.F., Fuchs T.A. et al. Impact of monochromatic coronary computed tomography angiography from single-source dual-energy CT oncoronary stenosis quantification. J Cardiovasc Comput Tomogr. 2016;10(2):135-140.

19.   DanadI., Hartaigh B., Min J.K. Dual-energy computed tomography for detection of coronary artery disease. Expert Rev Cardiovasc Ther. 2015;13(12):1345- 1356.

20.   Petranovic M., Soni A., Bezzera H. et al. Assessment of nonstenotic coronary lesions by 64-slice multidetector computed tomography in comparison to intravascular ultrasound: evaluation of nonculprit coronary lesions. J Cardiovasc. Comput. Tomogr. 2009;3(1):24-31.

21.   Leber A.W., Knez A., Becker A. et al. Accuracy of multidetector spiral computed tomography in identifying and differentiating the composition of coronary atherosclerotic plaques: a comparative study with intracoronary ultrasound. J. Am. Coll. Cardiol. 2004;43(7):1241-1247.

22.   Wu Y, Zheng M., Zhao H. et al. Low-concentration contrast material for dual-source computed tomography coronary angiography by a combination of iterative reconstruction and low-tube-voltage technique: feasibility study. Zhonghua YiXueZaZhi. 2014;94(29):2260-2263.

 

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