Abstract: Aim: was to study the diagnostic and prognostic importance of impedance indicators of a kidney parenchyma at acute (ARI) and chronic renal insufficiency (CRI). Material and methods. Research was performed on the basis of a hemodialysis department. 51 patients were examined during the period from 2009 till 2010. They underewent a monopolar bioimpedance measurement of kidneys under ultrasound control. Results. Changes of absolute and relative indicators of electric impedance of a kidney parenchyma show morphological violations in organ at acute and chronic renal insufficiency, characterize evidence of compensatory processes and give information on a tissue functional activity. These data are necessary for verification of the diagnosis, prescription of reasonable pharmacotherapy and definition of a pathological process forecast.