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Abstract:

Malignant otitis externa is a rare but potentially fatal disease, that occurs mostly among elderly diabetic or immunocompromised patients.

Aim: was is to report the experience of the diagnosis of malignant otitis externa.

Materials and methods: we examined 5 patients with diagnosed malignant otitis externa with the help of computed tomography (CT) and magnetic resonance imaging (MRI). In both diagnostic methods, contrast enhancement was used.

Results: causative pathogen is mainly Pseudomonas Aeruginosa. The disease spreads rapidly to skull base region, inducting osteomyelitis and involving the cranial nerves. The diagnosis is based on the radiology methods, anamnesis, and biopsy

Conclusions: CT is a first-line method, which allows to detect the presence of bone erosion, which is critical for the diagnosis. Exact borders of a pathological infiltration, distribution on cranial nerves, brain covers and in a skull were defined on MRI. 

 

References

1.     Rosenfeld R.M., Brown L., Cannon C.R., et al. Clinical practice guideline: acute otitis externa. Otolaryngol. Head Neck Surg. 2006; 134 (4): 4-23.

2.     Sander R. Otitis externa: a practical guide to treatment and prevention. Am Fam. Physician. 2001; 1;63(5): 927-36.

3.     Franco-Vidal V., Blanchet H., Bebear C., et al. Necrotizing external otitis: a report of 46 cases. Otol Neurotol. 2007; 28:771-3.

4.     Meltzer P.E., Kelemen G. Pyocutaneous osteomyelitis of the temporal bone, mandible, and zygoma. Laryngoscope. 1959; 169: 1300-16.

5.     Chandler J.R. Malignant external otitis. Laryngoscope. 1968; 78: 1257-94.

6.     Nadol J.B. Jr. Histopathology of pseudomonas osteomyelitis of the temporal bone starting as malignant external otitis. Am J Otolaryngol 1980; 1: 359-71.

7.     Matthew J. Carfrae, MD, Bradley W. et al. Malignant Otitis Externa. Otolaryngol Clin N Am. 2008; 41: 537-549.

8.     Rubin Grandis J., Branstetter B.F. 4th, Yu V.L. The changing face of malignant (necrotising) external otitis: clinical, radiological, and anatomic correlations. Lancet Infect Dis. 2004; 4: 34-9.

9.     Castro R., Robinson N., Klein J., et al. Malignant external otitis and mastoiditis associated with an IgG4 subclass deficiency in a child. Del Med J. 1990; 62: 1417-21.

10.   Holder C.D., Gurucharri M., Bartels L.J., et al. Malignant external otitis with optic neuritis. Laryngoscope. 1986; 96: 1021-3.

11.   Slattery W.H., Brackmann D.E. Skull base osteomyelitis: malignant otitis externa. Otolaryngol Clin North Am. 1996; 29: 795-806.

12.   Singh A., Al Khabori M., Hyder M.J. Skull base osteomyelitis: diagnostic and therapeutic challenges in atypical presentation. Otolaryngol Head Neck Surg. 2005; 133: 121-5.

13.   Bovo R., Benatti A., Ciorba A., et al. Pseudomonas and Aspergillus interaction in malignant external otitis: risk of treatment failure. Acta Otorhinolaryngol Ital. 2012; 32(6): 416-419.

14.   Meyers B.R., Mendelson M.H., Parisier S.C., et al. Malignant external otitis. comparison of monotherapy vs combination therapy. Arch Otolaryngol Head Neck Surg. 1987; 113: 974-8.

15.   Kwon B.J., Han M.H., Oh S.H., et al. MRI findings and spreading patterns of necrotizing external otitis: is a poor outcome predictable? Clin Radiol.2006; 61: 495-504.

16.   Grandis J.R., Curtin H.D., Yu V.L. Necrotizing (malignant) external otitis: prospective comparison of CT and MR imaging in diagnosis and follow-up. Radiology. 1995; 196: 499-504.

17.   Strashun A.M., Nejatheim M., Goldsmith SJ. Malignant external otitis: early scintigraphic detection. Radiology. 1984; 150: 541-5. 

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