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Abstract:

Aim: was to study CT semiotic features of hepatocellular carcinoma (HCC) with varying degrees of differentiation in liver, unaffected by cirrhosis.

Materials and methods: the study is based on clinical and morphological comparisons of 29 patients (19 men and 10 women aged 19-68 years) suffering from HCC without associated cirrhosis. In the preoperative period all patients underwent multislice CT with bolus contrast enhancement (on four phases of the study). On CT scans were determined: localization, size, borders and structure of nodes, including features of the accumulation of contrast agent for determining the degree of histological differentiation.

Results: HCC had the appearance of a large solitary node, the average value of the largest diameter and the cross-sectional area amounted to 9.3 cm and 68.4 cm2 respectively in most of examined patients. In the native phase of CT quite distinct contour of the tumor node was determined in 40% of cases at highly differentiated and one-third of moderately differentiated HCC observations, at poorly differentiated variant contour is not expressed.The characteristic feature of CT HCC nodes is the heterogeneous nature of their internal structure, which is best visualized in the arterial phase. Most frequently in observations (in 67.6%) were detected areas of necrosis, rarely observed lesions sclerosis (23.5%) and calcifications (11.8%).

Conclusion: Computed tomographic characteristics of HCC in the absence of cirrhosis depenc on the phase of the study, and the degree of histological differentiation of tumors that should be considered in the differential diagnosis and prognosis of the disease.

 

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