Website is intended for physicians
Search:

 

 

Abstract:

Aim: was to increase the level of differential diagnosis of thyroid nodules by evaluating their rigidity according to two ultrasound techniques - compressive elastography and shear wave elastography.

Materials and methods: study is based on the result of analysis of complex clinical anc ultrasound diagnostics, performed for the period from 2010 to 2015 , on the base of ultrasound department of «Central Clinical Hospital of Ministry of Internal Affairs» of the RF in Moscow, and Medical Radiological Research Center named after AF Tsyba - FGBU branch of «National Medical Research Radiological Center» MoH Obninsk.

Results: performed shear wave elastography, obtained quantitative data of rigidity of benign nodules and papillary carcinoma. Used methods of nonparametric statistics and ROC-analysis. Statistical processing was performed in SPSS 13.0 program. For benign nodes median of regidity was 15.6; 2,5-97,5 percentiles - 3,6-81,3; for papillary cancer: median 112.92; 2,5-97,5 percentiles - 13,5-196,4. Then followed an orange and yellow-red: blue color was not more than 20%, but mostly he was absent. In case of papillary cancer we observed two-color, three-color, four-color and six-color color, with prevailing of two colors - purple and blue.

Conclusions: both types of elastography - compressive and shear wave elastography - help to improve the differential diagnosis of thyroid cancer. Informativeness of shear wave elastography is higher, in comparison with compressive elastography.

 

References

1.     Kotljarov P.M., Harchenko V.P., Aleksandrov Ju.K., Mogunov  M.S., Sencha A.N., Patrunov Ju.N., Beljaev D.V. Ul'trazvukovaja diagnostika zabolevanij shhitovidnoj zhelezy [Ultrasonic diagnosis of thyroid diseases.]. M.: VIDAR. 2009: 239S [In Russ].

2.     Mit'kov V.V., Huako S.A., Cyganov S.E., Kirillova T.A., Mit'kova M.D. Sravnitel'nyj analiz dannyh jelastografii sdvigovoj volnoj i rezul'tatov morfologicheskogo issledovanija tela matki (predvaritel'nye rezul'taty) [Comparative analysis of data of shear wave elastography and results of uterine body morphological study (preliminary results)]. Ul'trazvukovaja i funkcional'naja diagnostika. 2013; 5: 99-114 [In Russ].

3.     Sencha A.N., Mogutov M.S., Patrunov U.N. et al. Kolichestvennie i kachastvennie pokazateli ul’trazvukovoi jelastografii v diagnostike raka shhitovidnoj zhelezy [Quantitative and qualitative indicators of ultrasound elastography in the diagnosis of thyroid cancer.]. Ul'trazvukovaja ifunkcional'naja diagnostika. 2013; 5: 85-98 [In Russ].

4.     Osipov L.V. Tehnologii jelastografii v ul’trazvukovoi diagnostike. Obzor. [ Elastography technologies in ultrasound diagnostics. Overview.] Diagnosticheskaya radiologiya i onkoterapiya. 2013; 3,4: 5-23 [In Russ].

5.     Parshin V.S., Yamasita C, Cib A.F. Zob. Ul'trazvukovaja diagnostika. Klinicheskii atlas [Ultrasound diagnostics. Clinical atlas]. Nagasaki-Obninsk. Universitet Nagasaki, 2000; S 106 [In Russ].

6.     Parshin V.S., Cib A.F., Yamasita C. Rak shhitovidnoj zhelezy. Ul'trazvukovaja diagnostika. Klinicheskii atlas [Thyroid cancer. Ultrasound diagnostics. A clinical atlas. In Chernobyl materials.]. Po materialam Cyernobilya. Obninsk. MRNC RAMN. 2002; S 230 [In Russ].

7.     Parshin V.S.,Yamashita S., Tsyb A.F. Ultrasound Diagnosis of Thyroid Diseases in Russia. Obninsk-Nagasaki. 2013; S147.

8.     Cib A.F., Parshin V.S., Yamasita C. Ul'trazvukovaja diagnostika zabolevanij shhitovidnoj zhelezy [Ultrasonic diagnosis of thyroid diseases.]. M.: Medicina. 1997; S 329 [In Russ].

9.     Asteria C., Giovanardi A., Pizzocaro A., Cozzaglio L., Morabito A., Somalvico F., Zoppo A. US-elastography in the differential diagnosis of benign and malignant thyroid nodules. Thyroid. 2008; 18: 523-531.

10.   Cantisani V., D'Andrea V., Biancari F., Medvedyeva O., Di Segni M., Olive M., Patrizi G., Redler A., De Antoni E.E., Masciangelo R., Frezzotti F., Ricci P Prospective evaluation of multiparametric ultrasound and quantitative elastosonography in the differential diagnosis of benign and malignant thyroid nodules: preliminary experience. Eur. J. Radiol. 2012; 81: 2678-2683.

11.   Vorlander C., Wolff J., Saalabian S., Lienenluke R.H., Wahl R.A. Real-time ultrasound elastographya non-invasive diagnostic procedure for evaluating dominant thyroid nodules Langenbecks Arch. Surg. 2010; 395: 865-871.

12.   Bojunga J., Herrmann E., Meyer G., Weber S., Zeuzem S., Friedrich-Rust M. Real-time elastography for the differentiation of benign and malignant thyroid nodules: a metaanalysis Thyroid. 2010; 20: 1145-1150.

13.   Gharib H., Papini E., Paschke R., Duick D.S., Valcavi R., Hegedus L., Vitti P American Association of Clinical Endocrinologists, Associazione Medici Endocrinologi and European Thyroid Association Medical Guidelines for Clinical Practice for the Diagnosis and Management of Thyroid Nodules. Endocr. Pract. 2010;16: 1-43.

14.   Moon H.J., Kim E.K., Yoon J.H., Kwak J.Y Clinical implication of elastography as a prognostic factor of papillary thyroid microcarcinoma. Ann. Surg. Oncol. 2012; 19: 2279-2287.

 

 

ANGIOLOGIA.ru (АНГИОЛОГИЯ.ру) - портал о диагностике и лечении заболеваний сосудистой системы