Abstract: The aim of the study was to assess the potential of nuclear imaging for long-term results assessment in myocardial infarction (MI) surgical treatment. 35 patients were included in the study: the main group (n = 15) of patients underwent bypass surgery in 3-4 weeks after MI, and the control group (n = 20) with conventional conservative MI treatment. Radionuclide angiopulmonography and radionuclide ECG-synchronized ventriculography was performed in all the patients in 1 month, 6 months, and 12 months after MI. Scintigraphic markers of post-operative complications were the following: (1) prolongation of minimal pulmonary circulation time 1 month after operation followed by (2) right chamber passage prolongation and (3) ejection fraction decrease. Stability of the mentioned parameters can serve as a predictor of smooth postoperative course. Feebleness of pulmonary circulation occurs earlier that the ejection fraction decrease, so it can be mentioned among the earliest symptoms of heart failure in patients with MI. Reference
1. Гиляревский С.Р., Орлов В.А., ГвинджилияТ.В. Коррекция постинфарктного ремоделирования сердца ингибиторами ангиотензинпревращающего фермента. Кардиология. 1993; 12: 37-47.
2. Mazzotta G., Vecchio С. Angiotensin converting enzyme inhibitors during acute phase ofmyocardial infarction. G. Ital. Cardiol. 1994;24 (1): 59-70.
3. McKay R.G., Pfeffer M.A., Pasternak R.C. et al. Left ventricular remodelling after myocardial infarction: a corollary to infarct expansion. Circulation. 1986; 74: 693-702.
4. Claes M.J., Vrints C.J., Bosmans J. et al.Corinary flow reserve during coronary angioplasty in patients with a recent myocardial infarction: relation to stenosis and myocardial viability.J. Am. Coll. Card. 1996; 28: 1712-1719.
5. Gersh B.J., Chesebro J.H., Braunwald E. et al.Coronary artery bypass graft surgery afterthrombolytic therapy in the Thrombolysis inMyocardial Infarction Trial, Phase II (TIMI II).J. Am. Coll. Card. 1995; 25 (2): 395-402.
6. Van`t Hof A.W.J., Liem A., Suryapranata H. etal. Clinical presentation and outcome of patients with early, intermediate and late reperfusion therapy by primary coronary angioplasty for acute myocardial infarction. Eur. Heart. J. 1998; 19: 118-123.
7. Goldberg R.J., Gore J.M., Alpert J.S. et al. Cardiogenic shock after acute myocardial infarction: incidence and mortality from a community-wide perspective, 1975 to 1988. N. Engl.J. Med. 1991; 325: 1117-1122.
8. Touboul P., Andre-Fouet X., Leizoroviczt A. et al. Risk stratification after myocardial infarction. Eur. Heart. J. 1997; 18: 99-107.
9. Taylor S.H. Congestive heart failure. Towards a comprehensive treatment. Eur. Heart. J. 1996; 17 (B): 43-56.
10. Матвеева Г.К. Артериальное давление в легочной артерии у больных ИБС, перенесших крупноочаговый и трансмуральный инфаркт миокарда, и его прогностическое значение. Aвтореф. дис. канд. мед. наук. М. 1988; 25. 11. Hakim T.S., Michel R.P. et al. Site of pulmonary hypoxic vasoconstriction studied with arterial and venous occlusion. / Appl. Physiol. 1983; 54 (5): 1298-1302.