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Abstract:

We present a clinical case, demonstrating the importance of x-ray technician compliance with rules of laying when performing x-ray examination of the mammary glands. According to the plain analog mammography with low quality, with positioning of not of all parts of the breast - the pathology was not revealed. In repeated mammographic study, conducted by all rules and all methodological aspects, in the upper-outer quadrant of the right breast, nodular newgrowth category BI-RADS 4c, highly suspicious on breast cancer was revealed. After the expansion of the diagnostic algorithm by echography and core-biopsy, low-differentiated breast cancer with high mitotic activity was verified.

 

Referenses

1.      Kaprin AD, Starinskiy V V, Petrova G V. Malignant neoplasms in Russia in 2017 (morbidity and mortality). М. 2018; 263 p [In Russ].

2.      Kanaev CV, Novikov SN, Semiglazov VF. Possibilities of early detection of breast cancer tumors using ultrasound and radionuclide diagnostic methods. Voprosy onkologii. 2011; 57(5): 622-626 [In Russ].

3.      Chernaya AV. Comparative analysis of informative value of digital mammography and mammoscintigraphy in breast cancer diagnostics. Dis. kand. med. nauk. SPb.: FGBU «NMITsO im. N. N. Petrova» MZ RF, 2018; 112 p [In Russ].

4.      Zuy VS, Solov'ev VI, Alieva FV., Garmot'ko AA, Nikitonova NV. Diagnostic sectoral resection as a method for verifying breast cancer in the Smolensk region (20102014). Vestnik Smolenskoy gosudarstvennoy meditsinskoyakademii. 2018; 17(2): 148-151 [In Russ].

5.      Rozhkova N I. The priority of women's health in the national program for the development of oncological services. Medicinskijalfavit. 2018; 2(29), (366): 6-9 [In Russ].

6.      Vasil’ev AYu., Мanuylova ОО. Stereoscopic mammography. An alternative method for the breast cancer early diagnosis. Radiologiya-praktika. 2017; 61(1): 6-14 [In Russ].

7.      Pavlova T V, Vasil'ev A Yu, Manuylova O O. Method of Сone-Вeam Breast Computed Tomography (Literature Review). Radiologiya - praktika. 2019;73(1): 21-27 [In Russ].

8.      Shumakova TA, Solntseva IA, Safronova OB, Savello VE, Serebryakova SV. The practical application of the international classification of Bi-RADS in mammology practice. Rukovodstvo dlya vrachey. SPb NII skoroy pomoshchi im. I.I.Dzhanelidze. SPb., 2018; 217 p. [In Russ].

9.      Sadykov S S, Bulanova Yu A, Zakharova E А. Methods of breast cancer detection. Algoritmy, metody i sistemy obrabotkidannykh. 2012;19(1): 168-178 [In Russ].

10.    Myakin'kov V B. World radiological experience. Radiologicheskiy visnik. 2012;44(3): 43-47 [In Russ].

 

Abstract:

Breast cancer is the most frequent malignant disease in women in the Russian Federation. To reduce the mortality from breast cancer, various measures were used, of which mammographic screening proved its effectiveness. In recent decades, the active process of informatization of health care system in the Russian Federation has predetermined the need to introduce various information systems, including in the screening processes. Thus, on the basis of Research Institute of Clinical and Experimental Radiology of the federal state budget institution «National Research Center of Oncology N.N.Blokhin» the Ministry of Health of the Russian Federation it was developed a system SDRR-MS (System Description, Recommendations and Reporting of Mammography Screening), which can be used both in screening and in diagnostic processes. The system focused on educational process and standardization of a routine practice of radiologists and X-ray technicians in the breast examination. The system allows to unite an unlimited number of hospitals, while standardization processes are realized by means of a formalized description protocol, elaborated on the basis of the existing international standard BI-RADS. This article is focused on one of system component, intended for the description of x-ray breast examination. 

  

References 

1.     Klinicheskie rekomendacii AOR po raku molochnoj zhelezy. Klinicheskie rekomendacii Associacii Onkologov Rossii [Recommendations of the AOR for breast cancer. Clinical recommendations of the Association of Oncologists of Russia.]. 2014; 84S [In Russ].

2.    Prikaz Ministerstva zdravoohranenija RF №36an ot 03 fevralja 2015 goda «Ob utverzhdenii porjadka provedenija dispanserizacii opredelennyh grupp vzroslogo naselenija» [Order of the Ministry of Health of the Russian Federation No. 36an of February 3, 2015 «On approval of the procedure for the clinical examination of certain groups of adults».] [In Russ] https://www.rosminzdrav.ru/documents/8542-prikazministerstva-zdravoohraneniya-rossiyskoy-federatsii-ot-3-fevralya- 2015-g-36an-ob-utverzhdenii-poryadkaprovedeniya-dispanserizatsii-opredelennyh-grupp-vzroslogo-naseleniya

3.     Kochergina N.V., Ivankina O.V., Zamogil'naja Ja.A., Bludov A.B. Pervye rezul'taty distancionnogo mammograficheskogo skrininga raka molochnoj zhelezy [First results of remote mammographic screening of breast cancer.]. Rossijskij onkologicheskijzhurnal. 2014; 3: 15-18 [In Russ].

4.     Kochergina N.V., Bludov A.B, Shhipahina Ja.A., Ivankina O.V. Novye napravlenija uluchshenija skrininga raka molochnoj zhelezy [New directions for improving of screening for breast cancer.] Vestnik rentgenologii i radiologii. 2016; 97(6): 333-339 [In Russ].

5.     Breast Cancer Surveillance Consortium (DCSC) http://www.bcsc-research.org/data/ptlong6.pdf

6.     Perri N. Evropejskoe rukovodstvo po obespecheniju kachestva pri skrininge i diagnostike raka molochnoj zhelezy [European guidelines for quality assurance in the screening and diagnosis of breast cancer.]. Health & Consumer Protection, Directorate-General. 2010. 4th edition [In Russ].

7.    Sinicyn V.E. Sistema opisanij i obrabotki dannyh issledovanija molochnoj zhelezy [Система описаний и обработки данных исследований груди.]. Mammologicheskij atlas. Izd. Medpraktika-M. 2010; 464S [In Russ].

8.     Metodicheskie rekomendacii k prikazu №154 ot 15 marta 2006 goda «O merah sovershenstvovanija medicinskoj pomoshhi pri zabolevanijah molochnoj zhelezy» [Methodical recommendations to the order number 154 from March 15, 2006 «On measures to improve medical care for breast diseases».] [In Russ].

9.     Koljadina I.V., Poddubnaja I.V., Komov D.V. Skrining raka molochnoj zhelezy:mirovoj opyt i perspektivy [Breast cancer screening: world experience and perspectives.] Rossijskij onkologicheskijzhurnal. 2015; 1:42-46 [In Russ].

10.   Poddubnaja I.V., Koljadina I.V., Kalashnikov N.D., Borisov A.A., Makarova M.V. Populjacinnyj cionnyj «portret» raka molochnoj zhelezy v Rossii: analiz dannyh rossijskogo registra [Population «portrait» of breast cancer in Russia: data analysis of the Russian register.]. Sovremennaja onkologija. 2015; 17(1):25-29 [ In Russ].

authors: 

 

Abstract:

Introduction of reconstructive-plastic operationts in practice of breast cancer surgical treatment have led to the necessity of dynamic monitoring methods development in patients after such treatment. We have proposed technique of mammography after reconstructive-plastic operations and operations with the use of silicone implants. For the period of 8 yrs 167 patients underwent dynamic mammography monitoring.

Proposed methodics allows to reliably assess the results of reconstructive-plastic operations and predict the appearance of possible complications.

 

Abstract:

We have performed a comparative analysis of magnetic resonance mammography (MRM) and traditional methods of diagnostics in detection of multifocal and multicentric kinds of breast cancer (BC) growth in 21 patients with difficult anatomy structure of mammary gland (MG) Breast-conserving surgery has been already planned for all these patients

Complex diagnostics included ultrasound(US), X-ray mammography (XRM), MRM with contrast enhancement, diagnostic needle biopsy Minimal size of identified breast tumors on the base of XRM data was 7 mm, ultrasound - 4 mm, at MR mammography - 2 mm XRM and US have detected multifocal tumor growth only in 1 case (5%). MRM revealed multifocal and multicentric tumor growth in 9 (43%) and 4 (19%) patients respectively According to revealed data the volume of surgical treatment has changed: 10 patients (48%) underwent radical resection, 10 (48%) mastectomy and 1 (5%) - partial resection

According to the conducted research it has been revealed that preoperative MR mammography is necessary for treatment planning in patients with breast cancer to avoid cancer recurrence after breast-conserving surgery.  

 

References 

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2.    Аблицова Н.В., Пак Д.Д., Сарибекян Э.К. Возможность выполнения органосохраняющих и реконструктивно-пластических операций при мультицентрическом раке молочной железы. Материалы II Всероссийской научно-практической конференции с международным участием «Научно-организационные аспекты и современные лечебно-диагностические технологии в маммологии». М., 2003; 176-177.

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9.    Drew P. et al. Dynamic contrast enhanced magnetic resonance imaging of the breast is superior to triple assessment for the preoperative detection of multifocal breast cancer. Ann. Surg. Oncol. 1999; 6: 599-603.

 

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13.  Houssami N. et al. Accuracy and surgical impact of MRI in breast cancer staging. Systematic review and meta-analysis in detection of multifocal and multicentric cancer. J. Clin. Oncol. 2008; 26: 3248-3258.

 

 

14.  Moon W.K., Noh D.Y., Im J.G. Multifocal, multicentric and contralateral breast cancers. Вilateral whole-breast US in the preoperative evaluation of patients. Radiology. 2002; 224: 569-576.

 

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Abstract:

The article describes main epidemiological, clinical and morphological diagnostic features of a rare form of breast tumor - hamartoma. Current scientific data accompany results of own seven-year research. Diagnostic features (qualitative elastography) of breast hamartoma are described for the first time ever. Authors draw attention to morphological diversity of the breast hamartoma, which leads to complex radiological semiotics. 

 

References

 

1.     Malignant diseases in Russia in 2011 (morbidity and mortality). Edited by V.I. Chissov. V.V. Starinsky, G.V. Petrova. M.: FSBI «P.A. Herzen MSROI of the Ministry of Health and Social Development of the Russia», 2013; 289.

 

2.     Tavassoli F.A., Devilee P. (Eds.): World Health Organization classification of Tumours. pathology and genetics of tumours of the breast and female genital organs. IARC Press: Lyon. 2003; 103.

3.     Prym P. Pseudoadenome, Adenome and Mastome der weinblichen Brustdruse uber die Entstehung umschriebener adenomahnlicher Herde in die Mamma und uber die Nachahmung des Brustdrusengewebes durch echte Adenome und Fibroadenome. Beitr. Pathol. Anat. Pathol. 1928; 81: 221.

4.     Arrigoni M.G., Dockerty M.B., Judd E.S. The identification and treatment of mammary hamartoma. Surg. Gynecol. Obstet. 1971; 133: 577-582.

5.     Ruiz-Tovar J., Reguero-Callejas M.E., Arano-Bermejo J.I. et al. Mammary hamartoma. Cir. Esp. 2006; 79 (3): 186-188.

6.     Lee W.F., Sheen-Chen S.M., Chi S.Y. et al. Hamartoma of the breast: an underrecognized disease? Tumori. 2008; 94 (1): 114-115.

7.     Farrokh D., Hashemi J., Ansaripour E. Breast hamartoma: Mammographic findings. Iran J. Radiol. 2011; 8 (4): 285-260.

8.     Mizuta N., Sakaguchi K., Mizuta M. et al. Myoid hamartoma of the breast that proved difficult to diagnose: a case report. World J. Surg. Oncol. 2012; 10 (12): URL: http:www.wjso.com/content/10/1/12.

9.     Ravakhah K., Javadi N., Simms R. Hamartoma of the breast in a man: first case report. Breast J. 2001; 7 (4): 266-268.

10.   Harigopal M., Mudrovich S.A., Hoda S.A., Rosen P.P. Secondary tumors in mammary adenolipomas: a report of 2 unusual cases. Arch. Pathol. Lab. Med. 2003; 127 (3): e151-e154.

11.   Murugesan J.R., Joglekar S., Valerio D. et al. Myoid hamartoma of the breast: case report and review of the literature. Clin. Breast Cancer. 2006; 7: 345-346.

12.   Ko M.-S., Jung W.S., Cha E.S., Choi H.J. A rare case of recurrent myoid hamartoma mimicking malignancy: imaging appearances. Korean J. Radiol. 2010; 11 (6): 683-686.

13.   Kajo K., Zubor P., Danko J. Myoid (muscular) hamartoma of the breast: case report and review of the literature. Breast care. 2010; 5: 331-334.

14.   Ayva S.K., Ozturk F.K., Obut H. Adenohibernoma: a rare breast tumor. Int. J. Surg. Pathol. 2012; 20 (3): 280-283.

15.   Nasit J.G., Parikh B., Trivedi P., Shah M. Myoid (muscular) hamartoma of the breast with chondroid metaplasia. Indian J. Pathol. Microbiol. 2012; 55: 121-122.

authors: 

 

Abstract:

Good response to neoadjuvant chemotherapy is a favorable prognostic factor in patients with breast cancer. Early response evaluation might spare unnecessary chemotherapy in bad responders. Clinically mammography and ultrasound are used to evaluate response to treatment while being bac predictors of early response. MRI is getting wider acceptance but still lacks necessary accuracy to the absence of functional evaluation. Thus novel methods are being evaluated in early response prediction. Diffusion-weighted MRI, MR-spectroscopy, mammoscintigraphy PET as well as diffusion optic tomography are discussed in the review as potential ways to improve early prediction of response in breast cancer patients undergoing neoadjuvant chemotherapy.

 

References

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2.     Montagna E., Bagnardi V., Rotmensz N. Pathological complete response after preoperative systemic therapy and outcome: relevance of clinical and biologic baseline features. Breast Cancer Res Treat. 2010;124(3):689-99.

3.     Bonnefoi H., Litiere S., Piccart M. Pathological complete response after neoadjuvant chemotherapy is an independent predictive factor irrespective of simplified breast cancer intrinsic subtypes: a landmark and two-step approach analyses from the EORTC 10994/BIG 1-00 phase III trial. Ann Oncol. 2014 Jun;25(6):1128-36.

4.     Semiglazov V.F., Paltuev R.M., Semiglazova TJu. i dr. Klinicheskie rekomendacii po diagnostike i lecheniju raka molochnoj zhelezy [Clinical guidelines for the diagnosis and treatment of breast cancer.]. SPb.: ABS-press. 2013; 234 [In Russ].

5.     Schmitt E.L., Threatt B.A. Effective breast cancer detection with filmscreen mammography. Canad. Ass. Radiol. 1985;36(4):303-307.

6.     Mistry K.A., Thakur M.H., Kembhavi S.A. The effect of chemotherapy on the mammographic appearance of breast cancer and correlation with histopathology. Brit. J. Radiol. 2016; 89:1057-1063.

7.     Helvie M.A., Joynt L.K., Cody R.L. et al. Locally advanced breast carcinoma: accuracy of mammography versus clinical examination in the prediction of residual disease after chemotherapy. Radiology. 1996;198:327-332.

8.    Komjahov A.V.. Ocenka jeffektivnosti neoad’juvantnoj sistemnoj terapii raka molochnoj zhelezy s pomoshhju magnitno-rezonansnoj tomografii i sonografii [Evaluation of the effectiveness of neoadjuvant systemic therapy for breast cancer using magnetic resonance imaging and sonography.]. Avtoreferat. Diss. kand. med. nauk SPb. 2016; 13-15 [In Russ].

9.    Gazhonova V.E., Efremova M.P., Dorohova E.A. Sovremennye metody neinvazivnoj luchevoj diagnostiki raka molochnoj zhelezy [Modern non-invasive methods of radiation diagnosis of breast cancer.]. RMZh. 2016;5:321-324 [In Russ].

10.  Meladze N.V., Ternovoj S.K., Abduraimov A.B. MR-spektroskopija v differencial'noj diagnostike uzlovyh obrazovanij molochnyh zhelez[MR spectroscopy in the differential diagnosis of nodular breast cancer.]. Bjulleten’ sibirskoj mediciny. 2012;5:78-79 [ In Russ].

11.   Semiglazov V.F., Semiglazov V.V., Krivorot'ko P.V. i dr. Rukovodstvo po lecheniju rannego raka molochnoj zhelezy [Guidelines for early breast cancer therapy.]. SPb. 2016; 12-13 [In Russ].

12.   Marinovich M.L., Macaskill P., Irwig L. et al. Metaanalysis of agreement between MRI and pathologic breast tumour size after neoadjuvant chemotherapy. Br. J. Cancer. 2013;109:1528-1536.

13.   Meladze N.V. Rol' Mr-spektroskopii v kompleksnoj diagnostiki raka molochnoj zhelezy [MR spectroscopy in the complex diagnosis of breast cancer]. Avtoreferat. Diss. kand. med. nauk. M. 2014;78-79 [In Russ].

14.   Danishad K.K., Sharma U., Sah R.G., et al. Assessment of therapeutic response of locally advanced breast cancer (LABC) patients undergoing neoadjuvant chemotherapy (NACT) monitored using sequential magnetic resonance spectroscopic imaging. NMR Biomed. 2010;23(3):233-41.

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