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Abstract: Aim: was to evaluate efficiency of stents-grafts in treatment of cerebral aneurysms. Materials and methods: for the period of 2001-2012 implantation of stent-grafts was performedm 10 patients with cerebral aneurysms. Indications for implantation: huge or giant aneurysms; wide«neck» of aneurysm; difficult localization for neurosurgical techniques; absence of significant tortuosity of artery that could interfere successful stent delivery All patients underwent examination: MSCT-angiography, MRI, cerebral angiography To predict possible stent thrombosis we performed angiographic tests with pinching of pathological artery and contrasting of opposite artery Then we assessed blood-flow of anterior and posterior communicating arteries and also changes in neurological status. Unsatisfactory condition of collateral blood-flow - was not a contraindication for stenting. In 8 patient, aneurysms were localized in internal carotid artery, and in 2 patients in the vertebrobasilar artery In 3 cases implantation of stent-graft was proceeded in acute period of hemorrhage; that caused late disaggregant therapy (immediately after implantation, drugs were injected through nasogastric tube instead of 4-5 days of preoperative treatment). Results: exclusion of the aneurysm from the blood-flow was reached 100% of cases. In one case, implantation of micro-coils was necessary due to inability to cover the whole neck of the aneurysm because of tortuosity of artery In 1 case we had thrombosis of stent in vertebral artery with spreading of thrombosis on basilar artery with development of ischemic stroke and further death. Conclusion: use of stent-grafts for exclusion of huge and giant aneurysms from cerebral blood- flow is a highly effective method. References 1. Zeb M., McKenzie D.B., Scott P.A., Talwar S. Treatment of coronary aneurysms with covered stents: a review with illustrated case. J. Invasive Cardiol. 2012; 24 (9): 465-469. 2. Briguori C., Nishida T., Anzuini A. et al. Emergency polytetrafluoroethylene-covered stent implantation to treat coronary ruptures. Circulation. 2000; 102 (25): 30283031. 3. Saatci I,.Cekirge H.S., Ozturk M.H. et al. Treatment of internal carotid artery aneurysms with a covered stent: experience in 24 patients with midterm follow-up results. AJNR Am. J. Neuroradiol. 2004; 25 (10): 1742-1749. 4. Hirurgija anevrizm golovnogo mozga. V 3 tomah. T. 1. Pod red. V.V. Krylova [Brain aneurysms surgery. In three volumes. Vol. 1. Edited by V.V. Krylov]. Moscow. 2012; 432S [In Russ]. 5. Tissen T.P., Jakovlev S.B. Bocharov A.V. Buharin E.Ju. Ispol'zovanie stent-grafta v jendovaskuljarnoj nejrohirurgii. Voprosy nejrohirurgii im. N.N. Burdenko [The use of stent-graft in endovascular neurosurgery]. 2006; 2: 53-56. [In Russ]. 6. Vulev I., Klepanec A., Bazik R. et al. Endovascular treatment of internal carotid and vertebral artery aneurysms using a novel pericardium covered stent. Interv. Neuroradiol. 2012; 18 (2): 164-171. 7. Greenberg E., Katz J.M., Janardhan V. et al. Treatment of a giant vertebrobasilar artery aneurysm using stent grafts. Case report. J. Neurosurg. 2007; 107 (1): 165-168. 8. Li M.H., Li YD., Tan H.Q. et al. Treatment of distal internal carotid artery aneurysm with the willis covered stent: a prospective pilot study. Radiology. 2009; 253 (2): 470-477. 9. Chalouhi N., Tjoumakaris S., Gonzalez L.F. et al. Coiling of large and giant aneurysms: complications and long-term results of 334 cases. AJNR Am. J. Neuroradiol. 2014; 35 (3): 546-452.