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Abstract:

In this study the potentialities of quantitative computed tomography (QCT) in bone densitometry is reported. QCT was performed in patients receiving glucocorticoid therapy and in postmenopausal women (55 patients all in all). Special software was used for the mineral density loss assessment: surrounding tissues were automatically subtracted, and calculating of the vertebral body density done in cross-sectional view. QCT allows specifying pathological changes in any vertebral structures and so serves as a good contribution to the diagnosis of osteoporosis. 

 

 

Reference

 

1.     Иванов Е.Г. Диагностика и лечение остеопороза. AW.J. Med. 2001; 90: 170-210.

2.     Насонов Е.Л., Скрипникова И.А., Насонова В.А. Проблема остеопороза в ревматологии. М.: Стин. 1997.

 

3.     Andresen R., Haidekker M. A., Radmer S.,Banzer D. CT determination of bone mineraldensity and structural investigations on the axial skeleton for estimating the osteoporosis-related fracture risk by means of a risk score. Br.J. Radiol. 1999; 72 (858): 569-578.

 

 

4.     Genant H. K., Guglielmi G., Jergas M. et al. Bone Densitometry and Osteoporosis. Springer. 1998; 604.

 

5.     Белосельский Н. Н. Рентгеновская морфометрия позвоночника в диагностике остеопороза. Остеопороз и остеопатии. 2000.

6.     Скрипникова И.А. Профилактика и лечение остеопороза. Материалы итоговойконференции по остеопорозу. Амстердам.1996.

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8.     Древаль А.В., Марченкова Л.Д., Мылов Н.М. Сравнительная информативность денситометрии осевого и периферического скелета и рентгенографии в диагностике постменопаузального остеопороза. Остеопороз и остеопатии. 1998; 2: 48-53.

9.     Оценка риска переломов и ее применение для скрининга постменопаузального остеопороза. Доклад Рабочей группы ВОЗ. Женева. 1994; 184.

10.   Benitez С. L., Schneider D. L., Barrett-Connor E., Sartoris D. J. Hand ultrasound for osteoporosis screening in postmenopausal women. Osteoporos. Int. 2000; 11 (3): 203-210.

11.   Krane St. M. Assessment of mineral and matrix turnover. In: B. Frame, J.T. Potts et al. Clinical disorders of bone and mineral metabolism. Excerpta medica. Internat. Congress Series 617. Amsterdam. Oxford, Princeton. 1983; 95-98.

 

Abstract:

Purpose. Was to investigate ability of videodensitometry for assessment the effect of renal artery stenosis on parenchymal perfusion.

Materials and methods. Аngiographic data of 97 patients with and 55 patients without renal artery stenosis were analyzed by means of videodensitometry, using «Multivox» software. All patients underwent renal arteries duplex ultrasound and kidneys ultrasound examination.

Levels of blood pressure and kidney function as a clinical signs of renovascular hypertension were assessed. Risk factors of kidney parenchymal injury such as diabetes mellitus, chronic kidney diseases were monitored.

Results. Videodensitometric analysis allows to detect statistically significant differences in parenchymal perfusion between kidneys with and without renal artery stenosis. A grade of changes in parenchymal perfusion correlates with angiographicaly measured degree of renal artery stenosis and renal artery blood flow velocity.

Conclusion. Videodensitometric perfusion parameters can be used to assess the effect of renal artery stenosis on parenchymal blood flow.

Thus, videodensitometry extends diagnostic capability of angiographic study. 

 

References 

 

1.    Hansen K.J. et al. Prevalence of renovascular desease in eldery. А populaton based study. J. Vasc. Surg. 2002; 36: 443–451.

 

 

2.    Safian R.D., Textor S.C. Renal artery stenosis. N. Engl. J. Med. 2001; 344: 431–442.

 

 

3.    Rihal C.S. et al. Incedental renal artery stenosis among a prospective cohort of hypertensive patients undergoing coronary angiography. May. Clin. Proc. 2002; 77:309–316.

 

 

4.    Olin J.W. et al. Prevalence of atherosclerotic RAS in patients with atherosclerosis else-where. Am. J. Med. 1990; 88: 46–51.

 

 

5.    Galaria I.I. et al. Percutaneous and open renal revascularizations have equivalent long-term functional outcomes. Ann. Vasc. Surgery. 2005; 19 (2): 218–228. 

 

 

 

6.    Weibull H. et al. Percutaneous transluminal renal angioplasty versus surgical reconstruction of atherosclerotic renal artery stenosis. А prospective randomized study.J. Vasc. Surg. 1993; 18: 841–850.

 

 

7.    Murphy T.P. et al. Increase of utilization of percutaneous renal artery interventions. Am.J. of Roentgenol. 2004; 183: 561–568.

 

 

8.    Wheatley K. et al. Revascularization versus medical therapy for renal artery stenosis. N.Engl. J. Med. 2009; 361: 1953–1962.  

 

 

9.    Rocha-Singh K.J. et al. Atherosclerotic Peripheral Vascular Disease Symposium II: Intervention for Renal Artery Disease. Circulation. 2008; 118: 2873–2878.

 

10.  Волынский Ю.Д., Кириллов М.Г., Шамалов Н.А. и др. Анализ экстра- и интракраниальной гемодинамики с помощью метода рентгеноденситометрии. Спец. выпуск «Инсульт». Ж. невр. и псих. им. С.С.Корсакова. 2007; 243.

 

 

11.  Meier P., Zierler K.L. On the theory of the indicator-dilution method for measurement of blood flow and volume. J. Appl. Physiol. 1954; 12: 731–744.

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