Biomechanics of left ventricle and left atrium in patients with mitral valve regurgitation

DOI: https://doi.org/10.25512/DIR.2018.12.2.02

For quoting:
Kulagina T.Y. , Khadzhieva D.R., Sandrikov V.A., Kouznetsova L.M. "Biomechanics of left ventricle and left atrium in patients with mitral valve regurgitation". Journal Diagnostic & interventional radiology. 2018; 12(2); 21-29.

authors:

Kulagina T.Y.

Khadzhieva D.R.

Sandrikov V.A.

Kouznetsova L.M.

keywords:

myocardium

deformation

speckle tracking imaging

left ventricle

left atrium

mitral insufficiency

Abstract:

Aim: to study the contractility of left ventricle (LV) and left atrium (LA) by speckle tracking imaging (STI), vector analysis and the diagram method in patients with mitral regurgitation (MR).

Materials and methods: we examined 63 patients (39 males, 24 females), mean age 53±11 years with 3-4 degree MR and control group of 26 healthy volunteers (15 males, 11 females), mean age 39±7 years. Transthoracic echocardiography was performed by a standard technique at rest. Sizes and volumes of LV, LA, ejection fraction (EF), degree of MR, pulmonary artery (PA) pressure were evaluated. LV and LA images were analyzed by STI with LV global longitudinal strain (GS), peak atrial longitudinal (PALS) and contraction strain (PACS), and by vector analysis of myocardial displacement and «Flow-Volume» diagrams. Rates of volume change in LV (dVol/dt) and LA (LAdVol/dt), rates of long axis change in LV (dLA/dt) and LA (LAdLA/dt), LA long axis size (LA) were calculated in systole (reservoir phase) and diastole (conduit phase). Statistical analysis (Statistica,10.0; JMP).

Results: left heart sizes and volumes, PA pressure compared to the norm were increased(p<0,(0)), but the EF was preserved. GS and PACS in patients with MR was normal, but PALS was reduced (p<0,(0)), while dVol/dt and LAdVol/dt were increased and shown in «Flow-Volume» diagrams. But, dLA/dt was normal, LAdLA/dt was reduced in the conduit phase, LA size was increased (p<0,(0)).

Conclusion: STI, vector analysis and diagram method parameters are the criteria for efficiency of LV and LA function in patients with MR.

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