Abstract

Background: advantages of endobiliary photodynamic therapy (PDT) described in the first part of review, namely: the safety of the intervention, the predictability and reproducibility of the effect, the absence of rough scarring of bile ducts, the possibility of repeating of procedures, affordability financially and economically - make this technology preferred among others locoregional effects in patients with hilus cholangiocarcinoma.

Aim: was to get a clinical specialist' view of endobiliary PDT as the perspective method: to describe dynamics of photosensitizer (PS) accumulation by tumor in vivo, to describe tools for delivering light into the lumen of bile ducts and intervention technique, to describe characteristics of light dosimetry, and to analyze immediate and long-term results of intra-duct photo exposure.

Material and methods: 66 domestic and foreign literary sources were analyzed.

Conclusion: endobiliary photodynamic therapy is a safe and effective method of locoregional treatment of patients with hilar cholangiocarcinoma, which significantly increases the duration and improves the quality of life of previously considered incurable patients.

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