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Abstract: We present a clinical case, demonstrating the importance of x-ray technician compliance with rules of laying when performing x-ray examination of the mammary glands. According to the plain analog mammography with low quality, with positioning of not of all parts of the breast - the pathology was not revealed. In repeated mammographic study, conducted by all rules and all methodological aspects, in the upper-outer quadrant of the right breast, nodular newgrowth category BI-RADS 4c, highly suspicious on breast cancer was revealed. After the expansion of the diagnostic algorithm by echography and core-biopsy, low-differentiated breast cancer with high mitotic activity was verified. Referenses 1. Kaprin AD, Starinskiy V V, Petrova G V. Malignant neoplasms in 2. Kanaev CV, Novikov SN, Semiglazov VF. Possibilities of early detection of breast cancer tumors using ultrasound and radionuclide diagnostic methods. Voprosy onkologii. 2011; 57(5): 622-626 [In Russ]. 3. Chernaya AV. Comparative analysis of informative value of digital mammography and mammoscintigraphy in breast cancer diagnostics. Dis. kand. med. nauk. SPb.: FGBU «NMITsO im. N. N. Petrova» MZ RF, 2018; 112 p [In Russ]. 4. Zuy VS, Solov'ev VI, Alieva FV., Garmot'ko AA, Nikitonova NV. Diagnostic sectoral resection as a method for verifying breast cancer in the 5. Rozhkova N I. The priority of women's health in the national program for the development of oncological services. Medicinskijalfavit. 2018; 2(29), (366): 6-9 [In Russ]. 6. Vasil’ev AYu., Мanuylova ОО. Stereoscopic mammography. An alternative method for the breast cancer early diagnosis. Radiologiya-praktika. 2017; 61(1): 6-14 [In Russ]. 7. Pavlova T V, Vasil'ev A Yu, Manuylova O O. Method of Сone-Вeam Breast Computed Tomography (Literature Review). Radiologiya - praktika. 2019;73(1): 21-27 [In Russ]. 8. Shumakova TA, Solntseva IA, Safronova OB, Savello VE, Serebryakova SV. The practical application of the international classification of Bi-RADS in mammology practice. Rukovodstvo dlya vrachey. SPb NII skoroy pomoshchi im. I.I.Dzhanelidze. SPb., 2018; 217 p. [In Russ]. 9. Sadykov S S, Bulanova Yu A, Zakharova E А. Methods of breast cancer detection. Algoritmy, metody i sistemy obrabotkidannykh. 2012;19(1): 168-178 [In Russ]. 10. Myakin'kov V B. World radiological experience. Radiologicheskiy visnik. 2012;44(3): 43-47 [In Russ].