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Аннотация: В обзоре предоставлены данные литературы о гепарин-индуцированной тромбоцитопении, её формах, патогенезе развития состояния и её клинических проявлениях. Рассмотрены варианты лечения этого осложнения и положения рекомендаций Американской коллегии врачей специалистов по заболеваниям органов грудной клетки (АССР), принятые на IX Конференции по антитромботической терапии и профилактике тромбозов в 2012 году. Список литературы 1. Kelton J.G., Warkentin T.E. Heparin-induced thrombocytopenia: a historical perspective. Blood. 2008; 112 (7): 2607-16. 2. Weismann R.E., Tobin R.W. Arterial embolism occurring during systemic heparin therapy. AMA Arch. Surg. 1958; 76 (2): 219-25; discussion 225-7. 3. Natelson E.A., Lynch E.C., Alfrey C.P., Gross J.B. Heparin-induced thrombocytopenia. An unexpected response to treatment of consumption coagulopathy. Ann. Intern. Med. 1969; 71 (6): 1121-5. 4. Rhodes G.R., Dixon R.H., Silver D. Heparin induced thrombocytopenia with thrombotic and hemorrhagic manifestations. Surg. Gynecol. Obstet. 1973; 136 (3): 409-16. 5. Jang I.K., Hursting M.J. When heparins promote thrombosis: review of heparin-induced thrombocytopenia. Circulation. 2005; 111 (20): 2671-83. 6. Greinacher A., Warkentin T.E. Heparin-induced thrombocytopenia. New York, N.Y: Marcel Dekker, 2004; 627 р. 7. Prechel М.М., Walenga М^ Emphasis on the Role of PF4 in the Incidence, Pathophysiology and Treatment of Heparin Induced Thrombocytopenia. Thrombosis Journal. 2013; 11:7. 8. Martel N., Lee J., Wells PS. Risk for heparin-induced thrombocytopenia with unfractionated and low-molecular-weight heparin thromboprophylaxis: a meta-analysis. Blood. 2005; 106 (8): 2710-15. 9. Warkentin T.E., Greinacher A. So, does low-molecular-weight heparin cause less heparin-induced thrombocytopenia than unfractionated heparin or not? Chest. 2007; 132 (4): 1108-10. 10. Warkentin T.E., Sheppard J.A., Sigouin C.S., et al. 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