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Abstract: According to current recommendations and orders of the Russian Ministry of Health, in the department of ultrasound diagnostics of the oncological center, it is necessary and lawfully to perform invasive manipulations to obtain a morphological verification of the oncological process. Nevertheless, there are significant gaps in the existing normative acts concerning organizational aspects. Aim: to conduct an analysis of the organization and results of morphological testing of malignant neoplasms in conditions of separation of ultrasonic diagnostics of the Kursk Regional Clinical Oncology Center. Materials and methods: 5,114 results of histological and immunohistochemical studies of material obtained with biopsies under ultrasound in the period 2012 - 2016 were analyzed. For the first time we included into department - 2 manipulation rooms, corresponding to sanitary requirements for conducting sterile manipulations. We first install Sonoscape S40 scanners in the manipulation rooms. All invasive examinations were performed by ambulatory and resident patients by ultrasound specialists who have a primary specialization in surgery, gynecology or urology Core biopsy was performed under local anesthesia with semi-automatic needles 14G or 16G; a gun-needle system biopsy was performed using a Bard-Magnum biopsy gun, Results. During the research, high efficiency of the proposed organizational model is revealed. A statistical relationship is revealed between the informativeness of the material and the physiciar who manipulates and organ-object. Ways of development are offered. References 1. Kaprin A.D., Starinskij V.V., Petrova G.V. The state of oncological care for the population of Russia in 2. Order of the Ministry of Health of the Russian Federation of 04.07.2017 No. 379n «On Amending the Procedure for the provision of medical care to the population in the field of oncology, approved by Order of the Ministry of Health of the Russian Federation of November15, 2012No.915n»].URL.:http://www.consultant.ru/document/cons_doc_LAW_220809/f891655c8c9f6864b656ef 38dba5a212e7e2b0e6/ (Data obrashhenija 23.10.2017) [In Russ]. 3. Chissov V.I., Dar'jalova S.L. [Oncology]. M.: «GJeOTAR-Media». 2007; 560 s [In Russ]. 4. Ponedel'nikova N.V., Korzhenkova G.P, Letjagin VP, Vishnevskaja Ja.V. Choice of the method of verifying the volume of newgrowth of the mammary gland at the preoperative stage. Opuholi zhenskoj reproduktivnoj sistemy. 2011; 1: 41-45 [In Russ]. 5. Nazarenko G.I., Hitrova A.N. Ultrasonic diagnostics of the prostate in modern oncological practice. M.: Izdatel'skij dom Vidar-M. 2012; 288s [In Russ]. 6. About the improvement of the service of radiation diagnosis: the order of the Ministry of Health of the RSFSR of August 2, 1991 № 132. URL.:http:// www.rasudm.org /information/docs.htm (Data obrashhenija 23.10.2017) [In Russ]. 7. Order of the Ministry of Health of the Russian Federation of December 27, 2011 N 1664n "ОП the approval of nomenclature of medical services". URL.:http://www.consultant.ru/cons/cgi/online.cgi?req=doc&base=LAW&n=27 8063&fld=134&dst=1,0&rnd=0.05494875175266367#0 (Data obrashhenija 04.11.2017) [In Russ]. 8. Decree of the Chief State Sanitary Doctor of the 10, 2016. URL.: http://base.garant.ru/12177989/ #ixzz4xU73XzAB (Data obrashhenija 04.11.2017) [In Russ]. 9. Attachment №2 to the order of the Ministry of Health of the 10. SPSS: the art of information processing. Analysis of statistical data and restoration of hidden regularities. Ahim Bjujul', Peter Cefel'.- DiaSoft, 2005; 608 s [In Russ].
Abstract: References 1. Kam Leung. [18F]Fluoro-2-deoxy-2-D-glucose in Molecular Imaging and Contrast Agent Database (MICAD). National Center for Biotechnology Information, NLM, NIH, Bethesda, MD. 2005. 2. Min-Fu Yang, Diwakar Jain, Zuo-Xiang He. 18F-FDG Cardiac Studies for Identifying Ischemic Memory. Curr Cardiovasc Imaging Rep. 2012; Dec, 5:383-389. 3. Ghesani M., Depuey E. G., Rozanski A. Role of F-18 FDG positron emission tomography (PET) in the assessment of myocardial viability. Echocardiography. 2005 Feb; 22(2): 165-77. 4. Nose H., Otsuka H., Otomi Y et al. Evaluation of normal physiologic left ventricular myocardial 18F-FDG uptake at fasting state. European Congress of Radiology. 2012. Vienna, Austria. URL: http://posterng.netkey.at/esr/ viewing/index.php?module=viewing_poster&doi=10.1594 /ecr2012/C-1192 2012. 5. Dong Soo Lee, Sang Kun Lee, Myung Chul Lee. Functional Neuroimaging in Epilepsy: FDG PET and Ictal SPECT. Korean Med Sci. 2001;16: 689-96. 6. Teune L. K., Bartels A. L., Leenders K. L. FDG-PET Imaging in Neurodegenerative Brain Diseases // Functional Brain Mapping and the Endeavor to Understand the Working Brain edited by Francesco Signorelli and Domenico Chirchiglia, 2013. 7. Sanchez-Catasis C. A., Vallez, Garcha D., Le Riverend Morales E., Galvizu Sбnchez R. Traumatic Brain Injury: Nuclear Medicine Neuroimaging .PET and SPECT in Neurology. 2014; 923-946. 8. Masangkay N., Basu S., Moghbel M. et al. Brain 18F-FDG-PET characteristics in patients with paraneoplastic neurological syndrome and its correlation with clinical and MRI findings. Nucl Med Commun. 2014 Oct; 35 (10): 1038-46. 9. Statistika zlokachestvennyh novoobrazovanij v Rossii i stranah SNG v 2012 g. Pod redakciej M.I. Davydova, E.M. Aksel'. [Statistics of malignant neoplasms in Russia and CIS countries in 2012. Edited by M.I. Davydova, E.M. Axel.] Moskva, 2014. - 226 s [In Russ]. 10. Jones S. C., Alavi A., Christman D. et al. The radiation dosimetry of 2 [F-18]fluoro-2-deoxy-D-glucose in man. J Nucl Med. 1982; 23, 613-617. 11. Kuwabara H., Gjedde A. Measurements of glucose phosphorylation with FDG and PET are not reduced by dephosphorylation of FDG-6-phosphate. J Nucl Med. 1991 Apr; 32(4): 692-8. 12. Data are from International Commission on Radiological Protection. Radiation Dose to Patients from Radiopharmaceuticals. St. Louis, MO. Elsevier; 2000:49. ICRP publication 80. 13. Ido T., Wan C. N., Fowler J. S. Fluorination with F2: convenient synthesis of 2-deoxy-2-fluoro-d-glucose. J Org Chem. 1977; 42: 2341-2. 14. Hamacher K., Coenen H. H., Stacklin G. Efficient stereospecific synthesis of no-carrier-added 2-[18F]- fluoro-2-deoxy-d-glucose using aminopolyether supported nucleophilic substitution. J Nucl Med. 1986; 27: 235-8. 15. Toorongian S. A., Mulholland G. K., Jewett D. M. et al. Routine production of 2-deoxy-2-[18F]fluoro-D- glucose by direct nucleophilic exchange on a quaternary 4-aminopyridinium resin. Int J Rad Appl Instrum B. 1990; 17 (3): 273-9. 16 Normy radiacionnoj bezopasnosti (NRB-99/2009). [Norms of radiation safety (NRB-99/2009).] SP 2.6.1.2523-09.[In Russ]. 17. Osnovnye sanitarnye pravila obespecheniya radiacionnoj bezopasnosti (OSPORB-99/2010). [Basic sanitary rules for ensuring radiation safety (0SP0RB-99/2010)]. SP 2.6.12612-10 [In Russ]. 18. SanPiN 2.6.1.3288-15 «Gigienicheskie trebovaniya po obespecheniyu radiacionnoj bezopasnosti pri podgotovke i provedenii pozitronnoj ehmissionnoj tomografii». [Hygienic requirements for ensuring radiation safety in the preparation and conduct of positron emission tomography.] [ In Russ]. 19. N.A. Gomzina, D.A. Vasil’ev, R.N. Krasikova. Optimization of Automated Synthesis of 2-[18F]Fluoro- 2-deoxy-D-glucose Involving Base Hydrolysis. Radiochemistry. 2002; 44 (4): 403-409. 20. Gopal B. Saha. Basics of PET Imaging: Physics, Chemistry and Regulations. - 3th ed. - New York: Springer International Publishing, 2016; 165.
Abstract: Aim: was to estimate the functionality of the nanokoloid drug labeled with technetium-99m for scintigraphy and intraoperative detection of «sentinel» lymph nodes (SLN) in experimental animals. Materials and methods: the study was performed in 6 series of experiments, including 5 white male rats line «Wistar» weighing 300-350 g. Injection of radiopharmaceuticals (RPh) at a dose of 18-20 MBq were performed between the first and second fingers of the front paws of rats. Results: in scintigraphic studies STL noted that RPh «Nanocolloid, 99mTc-Al2O3» accumulation reaches a plateau at the node (10.2%) for 2 hour study and its percentage content is stored at this level until 24 h. Intraoperative study, in all cases it was possible to visualize the STL. Conclusions: results shows functional fitness RPh «Nanocolloids,99mTc-Al2O3» for scintigraphy and intraoperative detection of «sentinel» lymph nodes.
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Acardiac fetus: postmortem computed and magnetic resonance tomography imaging
DOI: https://doi.org/10.25512/DIR.2016.10.2.03
For quoting:
Tumanova U.N., Fedoseeva V.K., Lyapin V.M., Bychenko V.G., Voevodin S.M., Shchegolev A.I. "Acardiac fetus: postmortem computed and magnetic resonance tomography imaging". Journal Diagnostic & interventional radiology. 2016; 10(2); 23-30.
Abstract: Acardiac fetus («acardiac monster», «acardiac vampire») - is rarely encountered pathology of pregnancy in which one of monochorionic fetuses (recipient) is formless mass, with absence of the heart and some internal organs, life and growth of which is related to parasitism on other fetus. The main reason for the formation of this defect is an abnormal location of placental vessels ir monochorionic twins. Characteristic are the underdevelopment of the upper body of the recipient fetus (underdevelopment of the upper part of chest, the absence of heart or the presence of rudimentary heart) and acephaly The article presents results of the analysis of the world literature data, and given own observation of acardiac fetus stillborn. We specify frequency causes, as well as the clinical and morphological features such anomalies. Possibilities of the post-mortem magnetic resonance and computed tomography imaging in determining the type of acardiac fetus. 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