Abstract: Article presents the results of analysis of risk factors associated with early stent thrombosis after percutaneous coronary intervention (PCI) ir patients with acute myocardial infarction (AMI). The study is designed as an observational cohort study prospectively including 140 patients with a PCI treated AMI admitted to our hospital. Patients were divided into two groups: with and without type 2 diabetes rnellitus (DM). A number of early stent thrombosis risk factors including a complete or not complete revascularization and myocardial blush grade during PCI, based on the predictive model were analyzed. The results of the study show that DM in patients with AMI who underwent PCI was not associated with a high risk of early stent thrombosis, however, incomplete revascularization was. References 1. Iakovou I., Schmidt T., Bonizzoni E., et al. Incidence, predictors, and outcome of thrombosis after successful implantation of drug-eluting stents. JAMA. 2005; 293: 2126-2130. 2. McFadden E. P., Stabile E., Regar E., et al. Late thrombosis in drug-eluting coronary stents after discontinuation of antiplatelet therapy. Lancet. 2004; 364: 1519-21. 3. Virmani R., Guagliumi G., Farb A., et al. Localized hypersensitivity and late coronary thrombosis secondary to a sirolimus-eluting stent: should we be cautious? Circulation. 2004; 109: 701-5. 4. Keith A.A., Philippe Gabriel Steg., Kim A. Eagle, et al. For the GRACE investigators decline in rates of death and heart failure in acute coronary syndromes. JAMA. 2007; 297: 1892-1900. 5. Iakovou I., Schmidt T., Bonizzoni E., Ge L. et al. Incidence, predictors, and outcome of thrombosis after successful implantation of drug-eluting stents. JAMA. 2005; 293(17): 2126-30. 6. Carr M. E. Diabetes mellitus: a hypercoagulable state. J. Diabetes Complications. 2001; 15: 44-54. 7. Georgios Sianos, Marie-AngMe Morel, Arie Pieter Kappetein The SYNTAX Score: an angiographic tool grading the complexity of coronary artery disease. Eurolnterv. 2005; 1: 219-227. 8. Petrosjan Ju S, Ioseliani D G. O summarnoj ocenke sostojanija koronarnogo rusla u bol'nyh ishemicheskoj bolezn'ju serdca. [Complex estimation of coronary arteries condition in patients with CAD.]. Kardiologija. 1976; 12(16): 41-46 [In Russ]. 9. Svilaas T. Thrombus aspiration during primary percutaneous coronary intervention. N. Engl. J. Med. 2008; 358: 557. 10. Mauri L., Hsieh W., Massaro J. M. et al. Stent thrombosis in randomized clinical trials of drug-eluting stents. N. Engl. J. Med. 2007; 356: 1020-9. 11. Rebrova O. Ju. Statisticheskij analiz medicinskih dannyh. [Statistic analysis of medical data]. Izd. Media Sfera. Moskva. 2003 [In Russ]. 12. Cockcroft D. W., Gault M. H. Prediction of creatinine clearance from serum creatinine. Nephron. 1976; 16: 31-41. 13. Norhammar A., Malmberg K., et al. Diabetes mellitus: the major risk factor in unstable coronary artery disease even after consideration of the extent of coronary artery disease and benefits of revascularization. J. Am. Coll. Cardiol. 2004; 43(4): 585-91. 14. Haim D. Danenberg, Greghana Marincheva, Boris Varshitzki, Hisham Nassar, Chaim Lotan Stent Thrombosis: A Poor Man's Disease? IMAJ. 2009; 11: 529-532. 15. Isaac Moscoso, Lazaro Claudiovino Garcia, Gilvan Oliveira Dourado, et al. Influence of Diabetes Mellitus on Immediate Results of Coronary Stent: 16. Aoki J., Lansky A. J., Mehran R. et al. Early stent thrombosis in patients with acute coronary syndromes treated with drug-eluting and bare metal stents: the Acute Catheterization and Urgent Intervention Triage Strategy trial. Circulation. Febr. 10, 2009; 119(5): 687-98. 17. Shaw R. E., Anderson. V., Brindis R.G. Development of a risk adjustment mortality model using the American College of Cardiology-National Cardiovascular Data Registry (ACC-NCDR) Experience: 1998-2000. J. Am. Coll. Cardiol. 2002; 39: 1104-12.
