Abstract: The work was aimed at determining the possibilities of multislice computed tomography (MSCT) in diagnosis and staging of acute pyelonephritis (AP) for studying the role of concomitant congenital renal anomalies in development of AP and therapeutic decision-making. A total of 59 patients presenting with AP and suspected pyodestructive complications were subjected to MSCT, with 7 seven of these having undergone it twice in order to control therapeutic efficacy. The study showed that ultrasonography as well as excretory urography are not always informative enough as to the possibility of revealing purulent forms of an inflammatory process having developed on the background of renal developmental defects, especially anomalies of the shape, localization, and structure. The obtained findings made it possible to define proper indications for performing MSCT in patients with AP. Improved diagnosis achieved by means of MSCT made it possible to decrease the number of operations and avoid unnecessary nephrectomies. Reference 1. Буйлов В.В., Крупин И.В., Тюзиков И.А. Алгоритмы ультразвукового сканирования экскреторной урографии при острых формах пиелонефрита (Екатеринбург, 15 - 18 октября 1996). М., 1996; 26-27. 2. Быковский В.А. Ультразвуковая диагностика острого пиелонефрита и его хирургических осложнений у детей. Дисс. канд. мед. наук. М., 1996. 3. Игнашин Н.С. Ультрасонография в диагностикеи лечении урологических заболеваний. М., 1997. 4. Пытель А.Я., Пытель Ю.А. Рентгендиагностика урологических заболеваний. М., 1966; 480. 5. Хитрова А.Н. Клиническое руководство по ультразвуковой диагностике. Т. 1 (Под ред. В.В. Митькова). М.: Издательский дом Видар-М, 1996; 200-256. 6. MМrild S., HellstrЪm M., Jacobsson B., et al: Influence of bacterial adhesion on ureteral width in children with acute pyelonephritis. J. Pediatr. 1989a; 115: 265-268. 7. Morin D., Veyrac C., Kotzki P., et al: Comparison of ultrasound and dimercaptosuccinic acid scintigraphy changes in acute pyelonephritis. Pediatr. Nephrol. 1999; 13:219-222. 8. Schaeffer A.J. Infections of the Urinary Tract. Campbell`s urology. 8th ed. Philadelphia, Saunders. 2002; (l): 515-603. 9. Shortliffe L. M. D. Urinary tract infections in infants and children. Campbell`s urology. 8th ed. Philadelphia, Saunders. 2002; (3): 1846-1885. 10. Назаренко Г.И., Хитрова А.Н., Краснова Т.В. Допплерографические исследования в уронефрологии. М.: Медицина, 2002; 49-55. 11. Чалый М.Е. Оценка органного кровообращения при урологических заболеваниях с применением эходопплерографии. Дисс. докт. мед. наук. М., 2005. 12. Чалый М.Е., Амосов А.В., Газимиев М.А. Диагностика острого пиелонефрита в послеоперационном периоде с применением цветной эходопплерографии. Материалы Пленума правления Российского общества урологов. (Киров, 20-22 июня). М., 2000; 105-106. 13. Dacher J.N., Pfister С, Monroe M., et al: Power Doppler sonographic pattern of acute pyelonephritis in children: Comparison with CT. AJR Am. J. Roentgenol. 1996; 166: 1451-1455. 14. Синякова Л.А. Гнойный пиелонефрит (современная диагностика и лечение). Дисс. докт. мед. наук. М., 2002. 15. Little P.J., McPherson D.R., Wardener H.E.: The appearance of the intravenous pyelogram during and after acute pyelonephritis. Lancet., 1965; 1: 1186. 16. Silver T.M., Kass E.J., Thornbury J.R., et al: The radiological spectrum of acute pyelonephritis in adults and adolescence. Radiology. 1976; 118: 65. 17. Barth K.H., Lightman N.I., Ridolfi R.L., et al: Acute pyelonephritis simulating poorly vascularized renal neoplasm, non-specificity of angiographic criteria. J. Urol. 1976; 116: 650. 18. Teplick J.G., Teplick S.K., Berinson H., et al: Urographic and angiographic changes in acute unilateral pyelonephritis. Clin. Radiol. 1978. 19. Тиктинский О.Л., Калинина С.Н. Пиелонефриты. СПб.: СПбМАПО, Медиа Пресс. 1996. 20. Baumgarten D.A., Baumgarten B.R. Imaging and radiologic management of upper urinary tract infec tions. Uroradiology. 1997; 24: 545. 21. Schaefer-Prokop C., Prokop M. Spiral and multislice tomography. Computed tomography of the body. Thieme, Stuttgard - New York. 2003; 641-678. 22. Фоминых Е.В. Мультиспиральная компьютерная томография в диагностике заболеваний мочевых путей. Дисс. канд. мед. наук, М., 2004.
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Abstract: Aim: the aim of this study was to evaluate the diagnostic possibilities of the dynamic MDCT in the differential diagnosis of gastric diseases compared with conventional upper gastrointestinal barium study and endoscopy Materials and methods: 130 patients with different gastric lesions underwent dynamic MDCT The detection rate of the gastric lesion and the diagnostic accuracy of each method were calculated by the use of surgical and histopathologic results as reference standards. Results: diagnostic accuracies of methods in the differential diagnosis of gastric tumors with exophytic growth were: endoscopy - 91%, barium study - 50%, MDCT - 87%; in the differential diagnosis of ulceration: endoscopy - 78%, barium study - 84%, MDCT - 93%; and in the diagnosis of diffuse type of gastric cancer: endoscopy - 82%, barium study - 75%, MDCT - 100%. Conclusion: integration of the dynamic MDCT in algorithms of diagnostics of gastric lesions can improve detection rates of stomach diseases and the accuracy of their differential diagnosis. References 1. Davidov M.I., Aksel’ E.M. The incidence of malignant tumors of the Russian population in 2009. Vestnik RONC N.N. Blokhina. 2011; 3(app 1): 60-65. 2. Портной Л.М., Вятчанин О.В., Сташук ГА. Новые взгляды на лучевую диагностику рака желудка (методико-семиотические и организационные аспекты). М.: Видар-М, 2004; 284 с. 3. Andaker L., Morales O., Hojer H., et al. Evaluation of preoperative computed tomograghy in gastric malignancy. Surgery. 1991; 109: 132-135. 4. Chen C-Y., Hsu J-S., Wu D-C., et al. Gastric cancer: preoperative local staging with 3D multi-detector row 5. Kim A.Y., Kim H.J., Ha H.K. Gastric cancer by multidetector row CT: preoperative staging. Abdom. Imaging. 2005; 30: 465-472. 6. Kim J.H., Eun H.W., Goo D.E., et al. Imaging of various gastric lesions with 2D MPR and CT gastrography performed with multi detect or CT. RadioGraphics. 2006; 26: 1101-1118. 7. Insko E.K., Levine M.S., Birnbaum B.A., Jacobs J.E. Benign and malignant lesions of the stomach: evaluation of CT criteria for differentiation. Radiology. 2003; 228: 166-171. 8. Ba-Ssalamah A., Prokop M., Uffmann M., et al. Dedicated multidetector CT of the stomach: spectrum of diseases. RadioGraphics. 2003; 23: 625-644. 9. Бурдюков М.С., Нечипай А.М., Чистякова О.В., Юричев И.Н., Ульянов Д.Н. Тонкоигольная пункция под контролем эндоскопической ультрасонографии в онкологической практике. Диагностическая и интервенционная радиология, 2007; 1(4): 19-30. 10. Gurin N.N., Logunov K.V. The effectiveness of differential diagnosis of benign and malignant gastric ulcers by endoscopy. Terapevticheskii arhiv. 1998; 4: 37-40. 11. Черноусов А.Ф., Волынчик К.Е. Роль хронической язвы желудка в канцерогенезе. Рос. журн. гастроэнтерол., гепатол. и колопроктол. 2004; 3: 53-59. (Chernousov A.F., Volinchik K.E. The role of chronic gastric ulcer in carcinogenesis. Rossiiskii gurnal gastroenterologii, gepatologii i koloproktologii. 2004; 3: 53-59). 12. Voutilainen M.E., Juhola M.T. Evaluation of the diagnostic accuracy of gastroscopy to detect gastric tumours: clinicopathological features and prognosis of patients with gastric cancer missed on endoscopy. Eur. J. Gastroenterol. Hepatol. 2005; 17(12): 1345-9. 13. Kim Y.N., Choi D., Kim S.H., et al. Gastric cancer staging at isotropic MDCT including coronal and sagittal MPR images: endoscopically diagnosed early vs. advanced gastric cancer. Abdom. Imaging. 2009; 34: 26-34.